A Clinical Guide to Gluten-Related Disorders by Alessio Fasano, Dr. Alessio Fasano MD

By Alessio Fasano, Dr. Alessio Fasano MD

A scientific advisor to Gluten-Related problems offers fundamental health and wellbeing care companies the succinct fabric they should instantly overview and help their sufferers. Gluten-related problems have a large presentation, and this article covers the popularity, overview, and multi-disciplinary method of the administration of ailment. Readers will enjoy the normal review of gluten intolerance and from the common Read more...

summary: A medical consultant to Gluten-Related issues presents fundamental wellbeing and fitness care prone the succinct fabric they should instantly overview and help their sufferers. Gluten-related problems have a large presentation, and this article covers the popularity, review, and multi-disciplinary method of the administration of ailment. Readers will enjoy the common evaluate of gluten intolerance and from the commonsense method of constructing remedy and nutritional plans. medical vignettes provide clinicians real-life situations to aid placed the sickness and its therapy in context for his or her sufferers

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Maki M, Mustalahti K, Kokkonen J, et al. Prevalence of celiac disease among children in Finland. N Engl J Med. 2003;348:2517–2524. 8. Tatar G, Elsurer R, Simsek H, et al. Screening of tissue transglutaminase antibody in healthy blood donors for celiac disease screening in the Turkish population. Dig Dis Sci. 2004;49:1479–1484. 9. Fasano A, Berti I, Gerarduzzi T, et al. Prevalence of celiac disease in at-risk and not-at-risk groups in the United States: A large multicenter study. Arch Intern Med.

After birth, infant feeding practices are important: Breast-feeding appears to have a protective role, while timing and amount of gluten at the time of its introduction also play a role. Furthermore, viral infections also appear to be important in the development of CD in genetically at-risk individuals. As indicated, mode of delivery has been studied as a possible risk factor for CD perhaps due to altered exposure to commensal bacteria in the perinatal period. 56 In a speculative article, Akobeng and Heller57 calculated that if all infants were breastfed for up to 1 year, in England and Wales there would be 2,655 fewer cases of CD.

NKG2D) on CD8+ intraepithelial lymphocytes (IELs). The T cell response arising in the lamina propria is also required to confer a fully activated phenotype to IELs through a mechanism that is already poorly understood. The co-operation between the responses arising in the two compartments (epithelium and lamina propria) leads finally to the development of villous atrophy, typical of CD mucosa. 114 Several approaches have been proposed for alternative CD treatment. Available generic drugs could find a new potential use in CD treatment; new drugs may also be developed, and few more are undergoing clinical trials.

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